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High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb
Human pathophysiology of high altitude hypoxic brain injury is not well understood and research on the underlying mechanisms is hampered by the lack of well-characterized animal models. In this study, we explored the evolution of brain injury by magnetic resonance imaging (MRI) and histological meth...
Autores principales: | Hoffmann, Angelika, Kunze, Reiner, Helluy, Xavier, Milford, David, Heiland, Sabine, Bendszus, Martin, Pham, Mirko, Marti, Hugo H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749302/ https://www.ncbi.nlm.nih.gov/pubmed/26863147 http://dx.doi.org/10.1371/journal.pone.0148441 |
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