Cargando…

PCDH8 is Frequently Inactivated by Promoter Hypermethylation in Liver Cancer: Diagnostic and Clinical Significance

AIM: Protocadherin-8 (PCDH8) plays an important role in signaling pathways of cell adhesin, proliferation, and migration. It has been reported that PCDH8 is mutated or methylated in several human cancers. However, little is known about PCDH8 in liver cancer. The aim of this study was to investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Cheng, Peng, Yunfei, Yang, Fan, Qin, Ruixi, Liu, Wenjun, Zhang, Cuijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749365/ https://www.ncbi.nlm.nih.gov/pubmed/26918058 http://dx.doi.org/10.7150/jca.13065

Ejemplares similares

PCDH18 is frequently inactivated by promoter methylation in colorectal cancer
por: Zhou, Dan, et al.
Publicado: (2017)

Frequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastoma
por: Lázcoz, Paula, et al.
Publicado: (2006)

TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma
por: Wang, Shumin, et al.
Publicado: (2010)

Clinical significance of protocadherin 8 (PCDH8) promoter methylation in non-muscle invasive bladder cancer
por: Lin, Ying-Li, et al.
Publicado: (2014)

Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
por: Zhang, Zuping, et al.
Publicado: (2008)

The Clinical Significance and Biological Function of PCDH7 in Cervical Cancer
por: Zhang, Shitong, et al.
Publicado: (2021)

Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma
por: Xiao, Xue, et al.
Publicado: (2013)

Transgelin gene is frequently downregulated by promoter DNA hypermethylation in breast cancer
por: Sayar, Nilufer, et al.
Publicado: (2015)

Clinical significance of PCDH10 promoter methylation in diffuse large B-cell lymphoma
por: Huang, Wenting, et al.
Publicado: (2017)

Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival
por: Barton, C A, et al.
Publicado: (2010)

Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation
por: Tao, Yan-Fang, et al.
Publicado: (2014)

Aberrant promoter methylation of PCDH10 as a potential diagnostic and prognostic biomarker for patients with breast cancer
por: Liu, Wentao, et al.
Publicado: (2018)

Downregulation of ADAMTS8 by DNA Hypermethylation in Gastric Cancer and Its Clinical Significance
por: Chen, Jing, et al.
Publicado: (2016)

E-cadherin promoter hypermethylation may contribute to protein inactivation in pterygia
por: Young, Chi-Hsien, et al.
Publicado: (2010)

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

Comparative characterization of PCDH19 missense and truncating variants in PCDH19-related epilepsy
por: Shibata, Mami, et al.
Publicado: (2020)

Aberrant Promoter Methylation of PCDH17 (Protocadherin 17) in Serum and its Clinical Significance in Renal Cell Carcinoma
por: Lin, Ying-Li, et al.
Publicado: (2017)

Hypermethylation of MEG3 promoter correlates with inactivation of MEG3 and poor prognosis in patients with retinoblastoma
por: Gao, Yali, et al.
Publicado: (2017)

Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi
por: Walesch, Sara K., et al.
Publicado: (2015)

Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies
por: Zorzan, Eleonora, et al.
Publicado: (2022)

Mosaicism and incomplete penetrance of PCDH19 mutations
por: Liu, Aijie, et al.
Publicado: (2019)

Clinical significance of DAPK promoter hypermethylation in lung cancer: a meta-analysis
por: Li, Ying, et al.
Publicado: (2015)

Promoter Hypermethylation of KLF4 Inactivates Its Tumor Suppressor Function in Cervical Carcinogenesis
por: Yang, Wen-Ting, et al.
Publicado: (2014)

Dual MGMT inactivation by promoter hypermethylation and loss of the long arm of chromosome 10 in glioblastoma
por: Richard, Sophie, et al.
Publicado: (2020)

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma
por: Tong, Joanna H, et al.
Publicado: (2010)

Frequent hypermethylation of orphan CpG islands with enhancer activity in cancer
por: Bae, Min Gyun, et al.
Publicado: (2016)

Association of frequent hypermethylation with high grade histological subtype in lung adenocarcinoma
por: Ito, Yuki, et al.
Publicado: (2023)

Aberrant Promoter Methylation of Protocadherin8 (PCDH8) in Serum is a Potential Prognostic Marker for Low Gleason Score Prostate Cancer
por: Lin, Ying-Li, et al.
Publicado: (2017)

Brain calcifications and PCDH12 variants
por: Nicolas, Gaël, et al.
Publicado: (2017)

Protocadherin 8 (PCDH8) Inhibits Proliferation, Migration, Invasion, and Angiogenesis in Esophageal Squamous Cell Carcinoma
por: Yu, Hong, et al.
Publicado: (2020)

PCDH9 acts as a tumor suppressor inducing tumor cell arrest at G(0)/G(1) phase and is frequently methylated in hepatocellular carcinoma
por: Lv, Jun, et al.
Publicado: (2017)

PCDH7 Inhibits the Formation of Homotypic Cell-in-Cell Structure
por: Wang, Chenxi, et al.
Publicado: (2020)

MicroRNA-124-3p inhibited progression of nasopharyngeal carcinoma by interaction with PCDH8 and the inactivation of PI3K/AKT/mTOR pathway
por: Ye, Jiacai, et al.
Publicado: (2021)

Clinicopathological significance of p15 promoter hypermethylation in multiple myeloma: a meta-analysis
por: Wei, Bing, et al.
Publicado: (2016)

Frequent Epigenetic Suppression of Tumor Suppressor Gene Glutathione Peroxidase 3 by Promoter Hypermethylation and Its Clinical Implication in Clear Cell Renal Cell Carcinoma
por: Liu, Qianling, et al.
Publicado: (2015)

MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation
por: Groenendijk, Floris H., et al.
Publicado: (2010)

Promoter hypermethylation-mediated inactivation of multiple Slit-Robo pathway genes in cervical cancer progression
por: Narayan, Gopeshwar, et al.
Publicado: (2006)

PCDH9 suppresses melanoma proliferation and cell migration
por: Zhang, Jiaojiao, et al.
Publicado: (2022)

Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors
por: Lee, Na Keum, et al.
Publicado: (2016)

VHL inactivation without hypoxia is sufficient to achieve genome hypermethylation
por: Artemov, Artem V., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h7rlil8ug13avs3f0l5u0lrl1h