Cargando…

Soluble N-cadherin: A novel inhibitor of VSMC proliferation and intimal thickening

Reoccurrence of symptoms occurs in 30–50% of coronary artery disease patients receiving vein grafts or bare-metal stents due to intimal thickening (restenosis). Restenosis is caused by vascular smooth muscle cell (VSMC) migration and proliferation. New therapeutic approaches that reduce VSMC migrati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lyon, Cressida A., Wadey, Kerry S., George, Sarah J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749540/ https://www.ncbi.nlm.nih.gov/pubmed/26586312 http://dx.doi.org/10.1016/j.vph.2015.11.040

Ejemplares similares

Inhibition of N-cadherin retards smooth muscle cell migration and intimal thickening via induction of apoptosis
por: Lyon, Cressida A., et al.
Publicado: (2010)

Inhibition of Intimal Thickening By PRH (Proline-Rich Homeodomain) in Mice
por: Reolizo, Lien M., et al.
Publicado: (2023)

Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression
por: Lyon, Cressida A., et al.
Publicado: (2017)

Lysyl oxidase (LOX) limits VSMC proliferation and neointimal thickening through its extracellular enzymatic activity
por: Varona, Saray, et al.
Publicado: (2018)

EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability
por: Lyon, Cressida A, et al.
Publicado: (2014)

Carotid artery ligation induced intimal thickening and proliferation is unaffected by ageing
por: Brown, B. A., et al.
Publicado: (2017)

Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation
por: Hulin-Curtis, Sarah, et al.
Publicado: (2017)

Matrix-Binding, N-Cadherin–Targeting Chimeric Peptide Inhibits Intimal Thickening but Not Endothelial Repair in Balloon-Injured Carotid Arteries
por: Burke-Kleinman, Jonah, et al.
Publicado: (2023)

miRNA-145 inhibits VSMC proliferation by targeting CD40
por: Guo, Xin, et al.
Publicado: (2016)

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension
por: Sun, Hai-Jian, et al.
Publicado: (2017)

Effects of vitamin C treatment on collar-induced intimal thickening
por: Arun, Mehmet Zuhuri, et al.
Publicado: (2015)

Pitavastatin Regulates Ang II Induced Proliferation and Migration via IGFBP-5 in VSMC
por: Ha, Yu Mi, et al.
Publicado: (2015)

Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease
por: Burtenshaw, Denise, et al.
Publicado: (2019)

Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling
por: Liu, Ji-Ting, et al.
Publicado: (2021)

Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR
por: Lee, Kyung Young, et al.
Publicado: (2016)

Luteolin Inhibits Angiotensin II-Stimulated VSMC Proliferation and Migration through Downregulation of Akt Phosphorylation
por: Xu, Tongda, et al.
Publicado: (2015)

INCREASED ARTERY WALL STRESS POST-STENTING LEADS TO GREATER INTIMAL THICKENING
por: Timmins, Lucas H., et al.
Publicado: (2011)

Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation
por: Conant, Katherine, et al.
Publicado: (2017)

AKT Mediates Adiponectin-Dependent Regulation of VSMC Phenotype
por: Cullen, Abigail E., et al.
Publicado: (2023)

Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function
por: Hudson, Claire, et al.
Publicado: (2018)

Ferulic Acid Alleviates Atherosclerotic Plaques by Inhibiting VSMC Proliferation Through the NO/p21 Signaling pathway
por: Wu, Xiaoyun, et al.
Publicado: (2022)

Zinc Inhibits HIF-Prolyl Hydroxylase Inhibitor-Aggravated VSMC Calcification Induced by High Phosphate
por: Nagy, Annamária, et al.
Publicado: (2020)

Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
por: Okita, Tomonori, et al.
Publicado: (2022)

The relationship between wall shear stress distributions and intimal thickening in the human abdominal aorta
por: Bonert, Michael, et al.
Publicado: (2003)

PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2
por: Zhou, Yi, et al.
Publicado: (2016)

Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation
por: Wu, Wen, et al.
Publicado: (2019)

Paeonia lactiflora Extract Attenuating Cerebral Ischemia and Arterial Intimal Hyperplasia Is Mediated by Paeoniflorin via Modulation of VSMC Migration and Ras/MEK/ERK Signaling Pathway
por: Chen, Yuh-Fung, et al.
Publicado: (2013)

Local honokiol application inhibits intimal thickening in rabbits following carotid artery balloon injury
por: Wang, Yu, et al.
Publicado: (2018)

5′-tiRNA-Cys-GCA regulates VSMC proliferation and phenotypic transition by targeting STAT4 in aortic dissection
por: Zong, Tingyu, et al.
Publicado: (2021)

p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics
por: Sahún-Español, Álvaro, et al.
Publicado: (2022)

Thymol reduces oxidative stress, aortic intimal thickening, and inflammation-related gene expression in hyperlipidemic rabbits
por: Yu, Ya-Mei, et al.
Publicado: (2016)

Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA
por: Sun, Jiangbin, et al.
Publicado: (2012)

Ultrastructural Study of Platelet Behavior and Interrelationship in Sprouting and Intussusceptive Angiogenesis during Arterial Intimal Thickening Formation
por: Díaz-Flores, Lucio, et al.
Publicado: (2021)

BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate
por: Nagy, Annamária, et al.
Publicado: (2021)

SENP2 Promotes VSMC Phenotypic Switching via Myocardin De-SUMOylation
por: Liang, Min, et al.
Publicado: (2022)

Patients with unstable angina and myocardial infarction expose remote VSMC phenotype switch and alteration in the proliferation of smooth muscular cell in the aortic wall
por: Woo, Chin Cheng, et al.
Publicado: (2015)

Role of N-cadherin in proliferation, migration, and invasion of germ cell tumours
por: Bremmer, Felix, et al.
Publicado: (2015)

Pipoxolan Ameliorates Cerebral Ischemia via Inhibition of Neuronal Apoptosis and Intimal Hyperplasia through Attenuation of VSMC Migration and Modulation of Matrix Metalloproteinase-2/9 and Ras/MEK/ERK Signaling Pathways
por: Chen, Yuh-Fung, et al.
Publicado: (2013)

Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors
por: Niimi, Rui, et al.
Publicado: (2013)

Increased aerobic glycolysis is important for the motility of activated VSMC and inhibited by indirubin-3′-monoxime
por: Heiss, Elke H., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4g0iphnq04k43q8v0p1mf2k52p