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16p11.2 Deletion mice display cognitive deficits in touchscreen learning and novelty recognition tasks

Chromosomal 16p11.2 deletion syndrome frequently presents with intellectual disabilities, speech delays, and autism. Here we investigated the Dolmetsch line of 16p11.2 heterozygous (+/−) mice on a range of cognitive tasks with different neuroanatomical substrates. Robust novel object recognition def...

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Detalles Bibliográficos
Autores principales:	Yang, Mu, Lewis, Freeman C., Sarvi, Michael S., Foley, Gillian M., Crawley, Jacqueline N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749736/ https://www.ncbi.nlm.nih.gov/pubmed/26572653 http://dx.doi.org/10.1101/lm.039602.115

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