DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation

Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two a...

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Autores principales: Dhakal, B., D'Souza, A., Pasquini, M., Saber, W., Fenske, T. S., Moss, R. B., Drobyski, W. R., Hari, P., Abidi, M. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749780/
https://www.ncbi.nlm.nih.gov/pubmed/26941799
http://dx.doi.org/10.1155/2016/8503275
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author Dhakal, B.
D'Souza, A.
Pasquini, M.
Saber, W.
Fenske, T. S.
Moss, R. B.
Drobyski, W. R.
Hari, P.
Abidi, M. Z.
author_facet Dhakal, B.
D'Souza, A.
Pasquini, M.
Saber, W.
Fenske, T. S.
Moss, R. B.
Drobyski, W. R.
Hari, P.
Abidi, M. Z.
author_sort Dhakal, B.
collection PubMed
description Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure.
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spelling pubmed-47497802016-03-03 DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation Dhakal, B. D'Souza, A. Pasquini, M. Saber, W. Fenske, T. S. Moss, R. B. Drobyski, W. R. Hari, P. Abidi, M. Z. Case Rep Med Case Report Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure. Hindawi Publishing Corporation 2016 2016-01-28 /pmc/articles/PMC4749780/ /pubmed/26941799 http://dx.doi.org/10.1155/2016/8503275 Text en Copyright © 2016 B. Dhakal et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Dhakal, B.
D'Souza, A.
Pasquini, M.
Saber, W.
Fenske, T. S.
Moss, R. B.
Drobyski, W. R.
Hari, P.
Abidi, M. Z.
DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title_full DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title_fullStr DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title_full_unstemmed DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title_short DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation
title_sort das181 treatment of severe parainfluenza virus 3 pneumonia in allogeneic hematopoietic stem cell transplant recipients requiring mechanical ventilation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749780/
https://www.ncbi.nlm.nih.gov/pubmed/26941799
http://dx.doi.org/10.1155/2016/8503275
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