Cargando…

Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study

Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a ter...

Descripción completa

Detalles Bibliográficos
Autores principales: Basak, Silpi, Singh, Priyanka, Rajurkar, Monali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749793/
https://www.ncbi.nlm.nih.gov/pubmed/26942013
http://dx.doi.org/10.1155/2016/4065603
_version_ 1782415322140114944
author Basak, Silpi
Singh, Priyanka
Rajurkar, Monali
author_facet Basak, Silpi
Singh, Priyanka
Rajurkar, Monali
author_sort Basak, Silpi
collection PubMed
description Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a tertiary care hospital. Material and Methods. The clinical samples were cultured and bacterial strains were identified in the department of microbiology. The antibiotic susceptibility profile of different bacterial isolates was studied to detect MDR, XDR, and PDR bacteria. Results. The antibiotic susceptibility profile of 1060 bacterial strains was studied. 393 (37.1%) bacterial strains were MDR, 146 (13.8%) strains were XDR, and no PDR was isolated. All (100%) Gram negative bacterial strains were sensitive to colistin whereas all (100%) Gram positive bacterial strains were sensitive to vancomycin. Conclusion. Close monitoring of MDR, XDR, or even PDR must be done by all clinical microbiology laboratories to implement effective measures to reduce the menace of antimicrobial resistance.
format Online
Article
Text
id pubmed-4749793
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-47497932016-03-03 Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study Basak, Silpi Singh, Priyanka Rajurkar, Monali J Pathog Research Article Background and Objective. Antimicrobial resistance is now a major challenge to clinicians for treating patients. Hence, this short term study was undertaken to detect the incidence of multidrug-resistant (MDR), extensively drug-resistant (XDR), and pandrug-resistant (PDR) bacterial isolates in a tertiary care hospital. Material and Methods. The clinical samples were cultured and bacterial strains were identified in the department of microbiology. The antibiotic susceptibility profile of different bacterial isolates was studied to detect MDR, XDR, and PDR bacteria. Results. The antibiotic susceptibility profile of 1060 bacterial strains was studied. 393 (37.1%) bacterial strains were MDR, 146 (13.8%) strains were XDR, and no PDR was isolated. All (100%) Gram negative bacterial strains were sensitive to colistin whereas all (100%) Gram positive bacterial strains were sensitive to vancomycin. Conclusion. Close monitoring of MDR, XDR, or even PDR must be done by all clinical microbiology laboratories to implement effective measures to reduce the menace of antimicrobial resistance. Hindawi Publishing Corporation 2016 2016-01-28 /pmc/articles/PMC4749793/ /pubmed/26942013 http://dx.doi.org/10.1155/2016/4065603 Text en Copyright © 2016 Silpi Basak et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Basak, Silpi
Singh, Priyanka
Rajurkar, Monali
Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title_full Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title_fullStr Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title_full_unstemmed Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title_short Multidrug Resistant and Extensively Drug Resistant Bacteria: A Study
title_sort multidrug resistant and extensively drug resistant bacteria: a study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749793/
https://www.ncbi.nlm.nih.gov/pubmed/26942013
http://dx.doi.org/10.1155/2016/4065603
work_keys_str_mv AT basaksilpi multidrugresistantandextensivelydrugresistantbacteriaastudy
AT singhpriyanka multidrugresistantandextensivelydrugresistantbacteriaastudy
AT rajurkarmonali multidrugresistantandextensivelydrugresistantbacteriaastudy