Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications

Several animal and human studies have implicated CD4+ T helper 17 (Th17) cells and their downstream pathways in the pathogenesis of central nervous system (CNS) autoimmunity in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD), challenging the traditional Th1-Th2 paradigm....

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Detalles Bibliográficos
Autores principales: Passos, Giordani Rodrigues Dos, Sato, Douglas Kazutoshi, Becker, Jefferson, Fujihara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749822/
https://www.ncbi.nlm.nih.gov/pubmed/26941483
http://dx.doi.org/10.1155/2016/5314541

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