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Utilizing Natural and Engineered Peroxiredoxins As Intracellular Peroxide Reporters

It is increasingly apparent that nature evolved peroxiredoxins not only as H(2)O(2) scavengers but also as highly sensitive H(2)O(2) sensors and signal transducers. Here we ask whether the H(2)O(2) sensing role of Prx can be exploited to develop probes that allow to monitor intracellular H(2)O(2) le...

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Detalles Bibliográficos
Autores principales: Van Laer, Koen, Dick, Tobias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749873/
https://www.ncbi.nlm.nih.gov/pubmed/26810074
http://dx.doi.org/10.14348/molcells.2016.2328