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Reduced Binding of the Endolysin LysTP712 to Lactococcus lactis ΔftsH Contributes to Phage Resistance

Absence of the membrane protease FtsH in Lactococcus lactis hinders release of the bacteriophage TP712. In this work we have analyzed the mechanism responsible for the non-lytic phenotype of L. lactis ΔftsH after phage infection. The lytic cassette of TP712 contains a putative antiholin–pinholin sys...

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Detalles Bibliográficos
Autores principales: Roces, Clara, Campelo, Ana B., Escobedo, Susana, Wegmann, Udo, García, Pilar, Rodríguez, Ana, Martínez, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749879/
https://www.ncbi.nlm.nih.gov/pubmed/26904011
http://dx.doi.org/10.3389/fmicb.2016.00138