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IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation

The features that define autoreactive T helper (Th) cell pathogenicity remain obscure. We have previously shown that Th cells require the transcription factor Bhlhe40 to mediate experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Here, using Bhlhe40 reporter mice an...

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Detalles Bibliográficos
Autores principales:	Lin, Chih-Chung, Bradstreet, Tara R., Schwarzkopf, Elizabeth A., Jarjour, Nicholas N., Chou, Chun, Archambault, Angela S., Sim, Julia, Zinselmeyer, Bernd H., Carrero, Javier A., Wu, Gregory F., Taneja, Reshma, Artyomov, Maxim N., Russell, John H., Edelson, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749922/ https://www.ncbi.nlm.nih.gov/pubmed/26834156 http://dx.doi.org/10.1084/jem.20150568

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