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Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide
Type I interferon (IFN) is crucial in host antiviral defense. Previous studies have described the pleiotropic role of type I IFNs on innate and adaptive immune cells during viral infection. Here, we demonstrate that natural killer (NK) cells from mice lacking the type I IFN-α receptor (Ifnar(−/−)) o...
Autores principales: | Madera, Sharline, Rapp, Moritz, Firth, Matthew A., Beilke, Joshua N., Lanier, Lewis L., Sun, Joseph C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749923/ https://www.ncbi.nlm.nih.gov/pubmed/26755706 http://dx.doi.org/10.1084/jem.20150712 |
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