Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2

MSP2 is an intrinsically disordered protein that is abundant on the merozoite surface and essential to the parasite Plasmodium falciparum. Naturally-acquired antibody responses to MSP2 are biased towards dimorphic sequences within the central variable region of MSP2 and have been linked to naturally...

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Detalles Bibliográficos
Autores principales: Krishnarjuna, Bankala, Andrew, Dean, MacRaild, Christopher A., Morales, Rodrigo A. V., Beeson, James G., Anders, Robin F., Richards, Jack S., Norton, Raymond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749986/
https://www.ncbi.nlm.nih.gov/pubmed/26865062
http://dx.doi.org/10.1038/srep20613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749986/
https://www.ncbi.nlm.nih.gov/pubmed/26865062
http://dx.doi.org/10.1038/srep20613

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