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Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2
MSP2 is an intrinsically disordered protein that is abundant on the merozoite surface and essential to the parasite Plasmodium falciparum. Naturally-acquired antibody responses to MSP2 are biased towards dimorphic sequences within the central variable region of MSP2 and have been linked to naturally...
Autores principales: | Krishnarjuna, Bankala, Andrew, Dean, MacRaild, Christopher A., Morales, Rodrigo A. V., Beeson, James G., Anders, Robin F., Richards, Jack S., Norton, Raymond S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749986/ https://www.ncbi.nlm.nih.gov/pubmed/26865062 http://dx.doi.org/10.1038/srep20613 |
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