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Randomized, Multicenter, Double–Blind Study of the Safety and Efficacy of 1%D-3-Hydroxybutyrate eye drops for Dry Eye Disease
In a previous study, we demonstrated that topical D-beta-hydroxybutyrate ameliorates corneal epithelial erosion and superficial punctate keratopathy in a rat model of dry eye disease. In the current investigation, we performed a prospective, randomized, multicentre, double-blind, placebo-controlled...
Autores principales: | Kawakita, Tetsuya, Uchino, Miki, Fukagawa, Kazumi, Yoshino, Kenichi, Shimazaki, Seika, Toda, Ikuko, Tanaka, Mari, Arai, Hiroyuki, Sakatani, Keiko, Hata, Seiichiro, Okano, Takashi, Tsubota, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749988/ https://www.ncbi.nlm.nih.gov/pubmed/26865350 http://dx.doi.org/10.1038/srep20855 |
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