5-hydroxymethylcytosine loss is associated with poor prognosis for patients with WHO grade II diffuse astrocytomas

Currently, the reliable prognostic biomarkers for WHO grade II diffuse astrocytomas (DA) are still limited. We investigated the relations between the level of 5-Hydroxymethylcytosine (5hmC), an oxidated production of 5-methylcytosine (5mC) by the ten eleven translocated (TET) enzymes, and clinicopat...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Liu, Yifan, Zhang, Zhiwen, Li, Jie, Wan, Yi, Zhang, Liying, Wang, Yangmei, Li, Xia, Xu, Yuqiao, Fu, Xin, Zhang, Xiumin, Zhang, Ming, Zhang, Zhekai, Zhang, Jing, Yan, Qingguo, Ye, Jing, Wang, Zhe, Chen, Charlie Degui, Lin, Wei, Li, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749994/
https://www.ncbi.nlm.nih.gov/pubmed/26864347
http://dx.doi.org/10.1038/srep20882

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