Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster

The human DHRS4 gene cluster consists of DHRS4 and two immediately downstream homologous genes, DHRS4L2 and DHRS4L1, generated by evolutionarily gene-duplication events. We previously demonstrated that a head-to-head natural antisense transcript (NAT) of DHRS4, denoted DHRS4-AS1, regulates all three...

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Detalles Bibliográficos
Autores principales: Yang, Yingying, Su, Zhongjing, Song, Xuhong, Liang, Bin, Zeng, Fanxing, Chang, Xiaolan, Huang, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750091/
https://www.ncbi.nlm.nih.gov/pubmed/26864944
http://dx.doi.org/10.1038/srep20961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750091/
https://www.ncbi.nlm.nih.gov/pubmed/26864944
http://dx.doi.org/10.1038/srep20961

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