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Enhancer RNA-driven looping enhances the transcription of the long noncoding RNA DHRS4-AS1, a controller of the DHRS4 gene cluster
The human DHRS4 gene cluster consists of DHRS4 and two immediately downstream homologous genes, DHRS4L2 and DHRS4L1, generated by evolutionarily gene-duplication events. We previously demonstrated that a head-to-head natural antisense transcript (NAT) of DHRS4, denoted DHRS4-AS1, regulates all three...
Autores principales: | Yang, Yingying, Su, Zhongjing, Song, Xuhong, Liang, Bin, Zeng, Fanxing, Chang, Xiaolan, Huang, Dongyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750091/ https://www.ncbi.nlm.nih.gov/pubmed/26864944 http://dx.doi.org/10.1038/srep20961 |
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