Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the generation of iPSC biobanks. To address this issue we compared transcriptomic, epigenetic, and differentiation propensities of genetically matched...

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Detalles Bibliográficos
Autores principales: Kyttälä, Aija, Moraghebi, Roksana, Valensisi, Cristina, Kettunen, Johannes, Andrus, Colin, Pasumarthy, Kalyan Kumar, Nakanishi, Mahito, Nishimura, Ken, Ohtaka, Manami, Weltner, Jere, Van Handel, Ben, Parkkonen, Olavi, Sinisalo, Juha, Jalanko, Anu, Hawkins, R. David, Woods, Niels-Bjarne, Otonkoski, Timo, Trokovic, Ras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750096/
https://www.ncbi.nlm.nih.gov/pubmed/26777058
http://dx.doi.org/10.1016/j.stemcr.2015.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750096/
https://www.ncbi.nlm.nih.gov/pubmed/26777058
http://dx.doi.org/10.1016/j.stemcr.2015.12.009

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