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Comparative immunogenicity and structural analysis of epitopes of different bacterial L-asparaginases

BACKGROUND: E.coli type II L-asparaginase is widely used for treatment of acute lymphoblastic leukemia. However, serious side effects such as allergic or hypersensitivity reactions are common for L-asparaginase treatment. Methods for minimizing immune response on L-asparaginase treatment in human in...

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Detalles Bibliográficos
Autores principales:	Pokrovsky, Vadim S., Kazanov, Marat D., Dyakov, Ilya N., Pokrovskaya, Marina V., Aleksandrova, Svetlana S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750198/ https://www.ncbi.nlm.nih.gov/pubmed/26867931 http://dx.doi.org/10.1186/s12885-016-2125-4

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