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Regulation of the tumour suppressor PDCD4 by miR-499 and miR-21 in oropharyngeal cancers

BACKGROUND: The rates of oropharyngeal cancers such as tonsil cancers are increasing. The tumour suppressor protein Programmed Cell Death Protein 4 (PDCD4) has been implicated in the development of various human cancers and small RNAs such as microRNAs (miRNAs) can regulate its expression. However t...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoying, Gee, Harriet, Rose, Barbara, Lee, C. Soon, Clark, Jonathan, Elliott, Michael, Gamble, Jennifer R., Cairns, Murray J., Harris, Adrian, Khoury, Samantha, Tran, Nham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750294/
https://www.ncbi.nlm.nih.gov/pubmed/26867589
http://dx.doi.org/10.1186/s12885-016-2109-4