Pediatric stiff-person syndrome with renal failure

Stiff-person syndrome (SPS) is an autoimmune neuronitis with progressive myoclonus and stiffness. It is a rare but treatable disorder with few case reports in children. SPS is due to autoantibodies against the enzyme glutamic acid decarboxylase which is present in neuronal and nonneuronal tissues. T...

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Detalles Bibliográficos
Autores principales: Kumar, M. Veerendra, Savida, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750317/
https://www.ncbi.nlm.nih.gov/pubmed/26933366
http://dx.doi.org/10.4103/0976-3147.165352
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author Kumar, M. Veerendra
Savida, P.
author_facet Kumar, M. Veerendra
Savida, P.
author_sort Kumar, M. Veerendra
collection PubMed
description Stiff-person syndrome (SPS) is an autoimmune neuronitis with progressive myoclonus and stiffness. It is a rare but treatable disorder with few case reports in children. SPS is due to autoantibodies against the enzyme glutamic acid decarboxylase which is present in neuronal and nonneuronal tissues. This is the case report of an 8-year-old boy with clinical and investigational features suggestive of SPS with associated myoglobin-induced renal failure, who completely recovered with treatment.
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spelling pubmed-47503172016-03-01 Pediatric stiff-person syndrome with renal failure Kumar, M. Veerendra Savida, P. J Neurosci Rural Pract Case Report Stiff-person syndrome (SPS) is an autoimmune neuronitis with progressive myoclonus and stiffness. It is a rare but treatable disorder with few case reports in children. SPS is due to autoantibodies against the enzyme glutamic acid decarboxylase which is present in neuronal and nonneuronal tissues. This is the case report of an 8-year-old boy with clinical and investigational features suggestive of SPS with associated myoglobin-induced renal failure, who completely recovered with treatment. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4750317/ /pubmed/26933366 http://dx.doi.org/10.4103/0976-3147.165352 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kumar, M. Veerendra
Savida, P.
Pediatric stiff-person syndrome with renal failure
title Pediatric stiff-person syndrome with renal failure
title_full Pediatric stiff-person syndrome with renal failure
title_fullStr Pediatric stiff-person syndrome with renal failure
title_full_unstemmed Pediatric stiff-person syndrome with renal failure
title_short Pediatric stiff-person syndrome with renal failure
title_sort pediatric stiff-person syndrome with renal failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750317/
https://www.ncbi.nlm.nih.gov/pubmed/26933366
http://dx.doi.org/10.4103/0976-3147.165352
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