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Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years

BACKGROUND: Although gamma knife has been advocated for hemangioblastomas, it is not used widely by neurosurgeons. OBJECTIVE: We review our experience over 14 years in an attempt to define the role of stereotactic radiosurgery (SRS) in the management of hemangioblastomas. PATIENTS AND METHODS: A ret...

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Autores principales: Goyal, Nishant, Agrawal, Deepak, Singla, Raghav, Kale, Shashank Sharad, Singh, Manmohan, Sharma, Bhawani Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750333/
https://www.ncbi.nlm.nih.gov/pubmed/26933339
http://dx.doi.org/10.4103/0976-3147.172165
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author Goyal, Nishant
Agrawal, Deepak
Singla, Raghav
Kale, Shashank Sharad
Singh, Manmohan
Sharma, Bhawani Shankar
author_facet Goyal, Nishant
Agrawal, Deepak
Singla, Raghav
Kale, Shashank Sharad
Singh, Manmohan
Sharma, Bhawani Shankar
author_sort Goyal, Nishant
collection PubMed
description BACKGROUND: Although gamma knife has been advocated for hemangioblastomas, it is not used widely by neurosurgeons. OBJECTIVE: We review our experience over 14 years in an attempt to define the role of stereotactic radiosurgery (SRS) in the management of hemangioblastomas. PATIENTS AND METHODS: A retrospective study was conducted on all patients of hemangioblastoma who underwent SRS at our institute over a period of 14 years (1998–2011). Gamma knife plans, clinical history, and radiology were reviewed for all patients. RESULTS: A total of 2767 patients underwent gamma knife during the study period. Of these, 10 (0.36%) patients were treated for 24 hemangioblastomas. Eight patients (80%) had von Hippel-Lindau disease while two had sporadic hemangioblastomas. The median peripheral dose (50% isodose) delivered to the tumors was 29.9 Gy. Clinical and radiological follow-up data were available for eight patients. Of these, two were re-operated for persisting cerebellar symptoms. The remaining six patients were recurrence-free at a mean follow-up of 48 months (range 19–108 months). One patient had an increase in cyst volume along with a decrease in the size of the mural nodule. CONCLUSIONS: SRS should be the first option for asymptomatic hemangioblastomas. Despite the obvious advantages, gamma knife is not widely used as an option for hemangioblastomas.
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spelling pubmed-47503332016-03-01 Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years Goyal, Nishant Agrawal, Deepak Singla, Raghav Kale, Shashank Sharad Singh, Manmohan Sharma, Bhawani Shankar J Neurosci Rural Pract Original Article BACKGROUND: Although gamma knife has been advocated for hemangioblastomas, it is not used widely by neurosurgeons. OBJECTIVE: We review our experience over 14 years in an attempt to define the role of stereotactic radiosurgery (SRS) in the management of hemangioblastomas. PATIENTS AND METHODS: A retrospective study was conducted on all patients of hemangioblastoma who underwent SRS at our institute over a period of 14 years (1998–2011). Gamma knife plans, clinical history, and radiology were reviewed for all patients. RESULTS: A total of 2767 patients underwent gamma knife during the study period. Of these, 10 (0.36%) patients were treated for 24 hemangioblastomas. Eight patients (80%) had von Hippel-Lindau disease while two had sporadic hemangioblastomas. The median peripheral dose (50% isodose) delivered to the tumors was 29.9 Gy. Clinical and radiological follow-up data were available for eight patients. Of these, two were re-operated for persisting cerebellar symptoms. The remaining six patients were recurrence-free at a mean follow-up of 48 months (range 19–108 months). One patient had an increase in cyst volume along with a decrease in the size of the mural nodule. CONCLUSIONS: SRS should be the first option for asymptomatic hemangioblastomas. Despite the obvious advantages, gamma knife is not widely used as an option for hemangioblastomas. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4750333/ /pubmed/26933339 http://dx.doi.org/10.4103/0976-3147.172165 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Goyal, Nishant
Agrawal, Deepak
Singla, Raghav
Kale, Shashank Sharad
Singh, Manmohan
Sharma, Bhawani Shankar
Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title_full Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title_fullStr Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title_full_unstemmed Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title_short Stereotactic radiosurgery in hemangioblastoma: Experience over 14 years
title_sort stereotactic radiosurgery in hemangioblastoma: experience over 14 years
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750333/
https://www.ncbi.nlm.nih.gov/pubmed/26933339
http://dx.doi.org/10.4103/0976-3147.172165
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