Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil

Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained...

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Detalles Bibliográficos
Autores principales: do Nascimento, Valdinete Alves, de Souza, Victor Costa, Naveca, Felipe Gomes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Genome Announcement and Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750455/
https://www.ncbi.nlm.nih.gov/pubmed/26841048
http://dx.doi.org/10.1590/0074-02760150416
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author do Nascimento, Valdinete Alves
de Souza, Victor Costa
Naveca, Felipe Gomes
author_facet do Nascimento, Valdinete Alves
de Souza, Victor Costa
Naveca, Felipe Gomes
author_sort do Nascimento, Valdinete Alves
collection PubMed
description Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations.
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spelling pubmed-47504552016-02-11 Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil do Nascimento, Valdinete Alves de Souza, Victor Costa Naveca, Felipe Gomes Mem Inst Oswaldo Cruz Genome Announcement and Highlights Dengue virus (DENV) infections represent a significant concern for public health worldwide, being considered as the most prevalent arthropod-borne virus regarding the number of reported cases. In this study, we report the complete genome sequencing of a DENV serotype 4 isolate, genotype II, obtained in the city of Manaus, directly from the serum sample, applying Ion Torrent sequencing technology. The use of a massive sequencing technology allowed the detection of two variable sites, one in the coding region for the viral envelope protein and the other in the nonstructural 1 coding region within viral populations. Instituto Oswaldo Cruz, Ministério da Saúde 2016-02 /pmc/articles/PMC4750455/ /pubmed/26841048 http://dx.doi.org/10.1590/0074-02760150416 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Genome Announcement and Highlights
do Nascimento, Valdinete Alves
de Souza, Victor Costa
Naveca, Felipe Gomes
Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_full Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_fullStr Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_full_unstemmed Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_short Complete genome of a dengue virus serotype 4 strain from Amazonas, Brazil
title_sort complete genome of a dengue virus serotype 4 strain from amazonas, brazil
topic Genome Announcement and Highlights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750455/
https://www.ncbi.nlm.nih.gov/pubmed/26841048
http://dx.doi.org/10.1590/0074-02760150416
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