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Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy
High hydrostatic pressure (HHP) has been shown to induce immunogenic cell death of cancer cells, facilitating their uptake by dendritic cells (DC) and subsequent presentation of tumor antigens. In the present study, we demonstrated immunogenicity of the HHP-treated tumor cells in mice. HHP was able...
Autores principales: | MIKYŠKOVÁ, ROMANA, ŠTĚPÁNEK, IVAN, INDROVÁ, MARIE, BIEBLOVÁ, JANA, ŠÍMOVÁ, JANA, TRUXOVÁ, IVA, MOSEROVÁ, IRENA, FUČÍKOVÁ, JITKA, BARTŮŇKOVÁ, JIŘINA, ŠPÍŠEK, RADEK, REINIŠ, MILAN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750542/ https://www.ncbi.nlm.nih.gov/pubmed/26718011 http://dx.doi.org/10.3892/ijo.2015.3314 |
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