Improved sensitivity of an acid sphingomyelinase activity assay using a C6:0 sphingomyelin substrate

Short-chain C6-sphingomyelin is an artificial substrate that was used in an acid sphingomyelinase activity assay for a pilot screening study of patients with Niemann–Pick disease types A and B. Using previously published multiplex and single assay conditions, normal acid sphingomyelinase activity le...

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Detalles Bibliográficos
Autores principales: Chuang, Wei-Lien, Pacheco, Joshua, Cooper, Samantha, Kingsbury, Jonathan S., Hinds, John, Wolf, Pavlina, Oliva, Petra, Keutzer, Joan, Cox, Gerald F., Zhang, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750609/
https://www.ncbi.nlm.nih.gov/pubmed/26937397
http://dx.doi.org/10.1016/j.ymgmr.2015.04.001

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