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Multipurpose Prevention Approaches with Antiretroviral-Based Formulations

We compared the preclinical safety and efficacy of tenofovir (TFV) 1% gel with that of MZC gel [containing 50 μM MIV-150, 14 mM Zn(O(2)CCH(3))(2)(H(2)O)(2), and 3% carrageenan] through a series of in vitro, ex vivo, and in vivo assays. The two gels showed good antiviral therapeutic indexes (50% cyto...

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Detalles Bibliográficos
Autores principales:	Jean-Pierre, Ninochka, Barnable, Patrick, Kizima, Larisa, Rodríguez, Aixa, Seidor, Samantha, Cooney, Michael L., Clark, Meredith R., Doncel, Gustavo F., Robbiani, Melissa, Zydowsky, Thomas M., Teleshova, Natalia, Fernández-Romero, José A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750675/ https://www.ncbi.nlm.nih.gov/pubmed/26596943 http://dx.doi.org/10.1128/AAC.02468-15

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