Quantitative In Silico analysis of transient metabolism of acetaminophen and associated causes of hepatotoxicity in humans

PURPOSE: Although safe at therapeutic levels, excess intake of acetaminophen can lead to hepatic injury or acute liver failure (ALF). A number of different factors influence metabolism and hepatotoxicity of acetaminophen in patients. Three of the most important are a patient’s physiological response...

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Detalles Bibliográficos
Autores principales: Navid, Ali, Ng, David M, Stewart, Benjamin J, Wong, Sergio E, Lightstone, Felice C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750864/
http://dx.doi.org/10.1186/2193-9616-1-14

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