Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014

H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, and antigenic variants of different clades have been selected. In this study, the national stockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluated for the protective efficacy against H5N8 HPAI...

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Autores principales: GAMOH, Koichiro, NAKAMIZO, Mari, OKAMATSU, Masatoshi, SAKODA, Yoshihiro, KIDA, Hiroshi, SUZUKI, Shoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Avian Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751133/
https://www.ncbi.nlm.nih.gov/pubmed/26290130
http://dx.doi.org/10.1292/jvms.15-0324
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author GAMOH, Koichiro
NAKAMIZO, Mari
OKAMATSU, Masatoshi
SAKODA, Yoshihiro
KIDA, Hiroshi
SUZUKI, Shoko
author_facet GAMOH, Koichiro
NAKAMIZO, Mari
OKAMATSU, Masatoshi
SAKODA, Yoshihiro
KIDA, Hiroshi
SUZUKI, Shoko
author_sort GAMOH, Koichiro
collection PubMed
description H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, and antigenic variants of different clades have been selected. In this study, the national stockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluated for the protective efficacy against H5N8 HPAI virus isolated in Kumamoto prefecture, Japan, in April 2014. In the challenge test, all of the vaccinated chickens survived without showing any clinical signs and reduced virus shedding. It was concluded that the present stockpiled vaccine was effective against the H5N8 HPAI virus.
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spelling pubmed-47511332016-02-26 Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014 GAMOH, Koichiro NAKAMIZO, Mari OKAMATSU, Masatoshi SAKODA, Yoshihiro KIDA, Hiroshi SUZUKI, Shoko J Vet Med Sci Avian Pathology H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, and antigenic variants of different clades have been selected. In this study, the national stockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluated for the protective efficacy against H5N8 HPAI virus isolated in Kumamoto prefecture, Japan, in April 2014. In the challenge test, all of the vaccinated chickens survived without showing any clinical signs and reduced virus shedding. It was concluded that the present stockpiled vaccine was effective against the H5N8 HPAI virus. The Japanese Society of Veterinary Science 2015-08-20 2016-01 /pmc/articles/PMC4751133/ /pubmed/26290130 http://dx.doi.org/10.1292/jvms.15-0324 Text en ©2016 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Avian Pathology
GAMOH, Koichiro
NAKAMIZO, Mari
OKAMATSU, Masatoshi
SAKODA, Yoshihiro
KIDA, Hiroshi
SUZUKI, Shoko
Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title_full Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title_fullStr Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title_full_unstemmed Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title_short Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014
title_sort protective efficacy of stockpiled vaccine against h5n8 highly pathogenic avian influenza virus isolated from a chicken in kumamoto prefecture, japan, in 2014
topic Avian Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751133/
https://www.ncbi.nlm.nih.gov/pubmed/26290130
http://dx.doi.org/10.1292/jvms.15-0324
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