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A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering

To derive and validate a practical patient-specific dose protocol to obtain an image quality, expressed by the image noise, independent of patients’ size and a better radiation dose justification in coronary CT angiography (CCTA) using prospective ECG triggering. 43 patients underwent clinically ind...

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Autores principales: van Dijk, J. D., Huizing, E. D., Jager, P. L., Ottervanger, J. P., Knollema, S., Slump, C. H., van Dalen, J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751172/
https://www.ncbi.nlm.nih.gov/pubmed/26563107
http://dx.doi.org/10.1007/s10554-015-0802-z
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author van Dijk, J. D.
Huizing, E. D.
Jager, P. L.
Ottervanger, J. P.
Knollema, S.
Slump, C. H.
van Dalen, J. A.
author_facet van Dijk, J. D.
Huizing, E. D.
Jager, P. L.
Ottervanger, J. P.
Knollema, S.
Slump, C. H.
van Dalen, J. A.
author_sort van Dijk, J. D.
collection PubMed
description To derive and validate a practical patient-specific dose protocol to obtain an image quality, expressed by the image noise, independent of patients’ size and a better radiation dose justification in coronary CT angiography (CCTA) using prospective ECG triggering. 43 patients underwent clinically indicated CCTA. The image noise, defined as the standard deviation of pixel attenuation values in a homogeneous region in the liver, was determined in all scans. Subsequently, this noise was normalized to the radiation exposure. Next, three patient-specific parameters, body weight, body mass index and mass per length (MPL), were tested for the best correlation with normalized image noise. From these data, a new dose protocol to provide a less variable image noise was derived and subsequently validated in 84 new patients. The normalized image noise increased for heavier patients for all patients’ specific parameters (p < 0.001). MPL correlated best with the normalized image noise and was selected for dose protocol optimization. This new protocol resulted in image noise levels independent of patients’ MPL (p = 0.28). A practical method to obtain CCTA images with noise levels independent of patients’ MPL was derived and validated. It results in a less variable image quality and better radiation exposure justification and can also be used for CT scanners from other vendors.
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spelling pubmed-47511722016-02-22 A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering van Dijk, J. D. Huizing, E. D. Jager, P. L. Ottervanger, J. P. Knollema, S. Slump, C. H. van Dalen, J. A. Int J Cardiovasc Imaging Original Paper To derive and validate a practical patient-specific dose protocol to obtain an image quality, expressed by the image noise, independent of patients’ size and a better radiation dose justification in coronary CT angiography (CCTA) using prospective ECG triggering. 43 patients underwent clinically indicated CCTA. The image noise, defined as the standard deviation of pixel attenuation values in a homogeneous region in the liver, was determined in all scans. Subsequently, this noise was normalized to the radiation exposure. Next, three patient-specific parameters, body weight, body mass index and mass per length (MPL), were tested for the best correlation with normalized image noise. From these data, a new dose protocol to provide a less variable image noise was derived and subsequently validated in 84 new patients. The normalized image noise increased for heavier patients for all patients’ specific parameters (p < 0.001). MPL correlated best with the normalized image noise and was selected for dose protocol optimization. This new protocol resulted in image noise levels independent of patients’ MPL (p = 0.28). A practical method to obtain CCTA images with noise levels independent of patients’ MPL was derived and validated. It results in a less variable image quality and better radiation exposure justification and can also be used for CT scanners from other vendors. Springer Netherlands 2015-11-12 2016 /pmc/articles/PMC4751172/ /pubmed/26563107 http://dx.doi.org/10.1007/s10554-015-0802-z Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
van Dijk, J. D.
Huizing, E. D.
Jager, P. L.
Ottervanger, J. P.
Knollema, S.
Slump, C. H.
van Dalen, J. A.
A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title_full A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title_fullStr A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title_full_unstemmed A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title_short A practical approach for a patient-tailored dose protocol in coronary CT angiography using prospective ECG triggering
title_sort practical approach for a patient-tailored dose protocol in coronary ct angiography using prospective ecg triggering
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751172/
https://www.ncbi.nlm.nih.gov/pubmed/26563107
http://dx.doi.org/10.1007/s10554-015-0802-z
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