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A Simulation Model of Periarterial Clearance of Amyloid-β from the Brain
The accumulation of soluble and insoluble amyloid-β (Aβ) in the brain indicates failure of elimination of Aβ from the brain with age and Alzheimer's disease (AD). There is a variety of mechanisms for elimination of Aβ from the brain. They include the action of microglia and enzymes together wit...
Autores principales: | Diem, Alexandra K., Tan, Mingyi, Bressloff, Neil W., Hawkes, Cheryl, Morris, Alan W. J., Weller, Roy O., Carare, Roxana O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751273/ https://www.ncbi.nlm.nih.gov/pubmed/26903861 http://dx.doi.org/10.3389/fnagi.2016.00018 |
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