Cargando…
TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS
A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane metalloprotease that cleaves the extracellular regions from its transmembrane substrates. ADAM10 is essential for embryonic development and is implicated in cancer, Alzheimer, and inflammatory diseases. The tetra...
Autores principales: | Noy, Peter J., Yang, Jing, Reyat, Jasmeet S., Matthews, Alexandra L., Charlton, Alice E., Furmston, Joanna, Rogers, David A., Rainger, G. Ed, Tomlinson, Michael G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751363/ https://www.ncbi.nlm.nih.gov/pubmed/26668317 http://dx.doi.org/10.1074/jbc.M115.703058 |
Ejemplares similares
-
Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins
por: Matthews, Alexandra L., et al.
Publicado: (2017) -
Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential
por: Harrison, Neale, et al.
Publicado: (2021) -
Regulation of Leukocytes by TspanC8 Tetraspanins and the “Molecular Scissor” ADAM10
por: Matthews, Alexandra L., et al.
Publicado: (2018) -
TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life
por: Eschenbrenner, Etienne, et al.
Publicado: (2019) -
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals
por: Dornier, Emmanuel, et al.
Publicado: (2012)