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Endosulfan Induces CYP1A1 Expression Mediated through Aryl Hydrocarbon Receptor Signal Transduction by Protein Kinase C

CYP1A1 is a phase I xenobiotic-metabolizing enzyme whose expression is mainly driven by AhR. Endosulfan is an organochlorine pesticide used agriculturally for a wide range of crops. In this study, we investigated the effect of endosulfan on CYP1A1 expression and regulation. Endosulfan significantly...

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Detalles Bibliográficos
Autores principales: Han, Eun Hee, Kim, Hyung Gyun, Lee, Eun Ji, Jeong, Hye Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society Of Toxicology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751443/
https://www.ncbi.nlm.nih.gov/pubmed/26877836
http://dx.doi.org/10.5487/TR.2015.31.4.339