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Structure of ring-shaped Aβ(42) oligomers determined by conformational selection

The oligomerization of amyloid beta (Aβ) peptides into soluble non-fibrillar species plays a critical role in the pathogenesis of Alzheimer’s disease. However, it has been challenging to characterize the tertiary and quaternary structures of Aβ peptides due to their disordered nature and high aggreg...

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Detalles Bibliográficos
Autores principales: Tran, Linh, Basdevant, Nathalie, Prévost, Chantal, Ha-Duong, Tâp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751476/
https://www.ncbi.nlm.nih.gov/pubmed/26868929
http://dx.doi.org/10.1038/srep21429

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