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A Biotin Biosynthesis Gene Restricted to Helicobacter

In most bacteria the last step in synthesis of the pimelate moiety of biotin is cleavage of the ester bond of pimeloyl-acyl carrier protein (ACP) methyl ester. The paradigm cleavage enzyme is Escherichia coli BioH which together with the BioC methyltransferase allows synthesis of the pimelate moiety...

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Detalles Bibliográficos
Autores principales: Bi, Hongkai, Zhu, Lei, Jia, Jia, Cronan, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751477/
https://www.ncbi.nlm.nih.gov/pubmed/26868423
http://dx.doi.org/10.1038/srep21162