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Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans

Chromoanasynthesis is a recently discovered phenomenon in humans with congenital diseases that is characterized by complex genomic rearrangements (CGRs) resulting from aberrant repair of catastrophic chromosomal damage. How these CGRs are induced is not known. Here, we describe the structure and fun...

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Detalles Bibliográficos
Autores principales:	Itani, Omar A., Flibotte, Stephane, Dumas, Kathleen J., Moerman, Donald G., Hu, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751554/ https://www.ncbi.nlm.nih.gov/pubmed/26628482 http://dx.doi.org/10.1534/g3.115.024257

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