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Changes in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters

Sphingolipids are essential constituents of the plasma membrane (PM) and play an important role in signal transduction by modulating clustering and dynamics of membrane receptors. Changes in lipid composition are therefore likely to influence receptor organisation and function, but how this precisel...

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Detalles Bibliográficos
Autores principales: Eich, Christina, Manzo, Carlo, Keijzer, Sandra de, Bakker, Gert-Jan, Reinieren-Beeren, Inge, García-Parajo, Maria F., Cambi, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751618/
https://www.ncbi.nlm.nih.gov/pubmed/26869100
http://dx.doi.org/10.1038/srep20693