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Changes in membrane sphingolipid composition modulate dynamics and adhesion of integrin nanoclusters
Sphingolipids are essential constituents of the plasma membrane (PM) and play an important role in signal transduction by modulating clustering and dynamics of membrane receptors. Changes in lipid composition are therefore likely to influence receptor organisation and function, but how this precisel...
Autores principales: | Eich, Christina, Manzo, Carlo, Keijzer, Sandra de, Bakker, Gert-Jan, Reinieren-Beeren, Inge, García-Parajo, Maria F., Cambi, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751618/ https://www.ncbi.nlm.nih.gov/pubmed/26869100 http://dx.doi.org/10.1038/srep20693 |
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