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Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils,...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751725/ https://www.ncbi.nlm.nih.gov/pubmed/26904159 http://dx.doi.org/10.1186/s40413-016-0094-3 |
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| author | Metcalfe, Dean D. Pawankar, Ruby Ackerman, Steven J. Akin, Cem Clayton, Frederic Falcone, Franco H. Gleich, Gerald J. Irani, Anne-Marie Johansson, Mats W. Klion, Amy D. Leiferman, Kristin M. Levi-Schaffer, Francesca Nilsson, Gunnar Okayama, Yoshimichi Prussin, Calman Schroeder, John T. Schwartz, Lawrence B. Simon, Hans-Uwe Walls, Andrew F. Triggiani, Massimo |
| author_facet | Metcalfe, Dean D. Pawankar, Ruby Ackerman, Steven J. Akin, Cem Clayton, Frederic Falcone, Franco H. Gleich, Gerald J. Irani, Anne-Marie Johansson, Mats W. Klion, Amy D. Leiferman, Kristin M. Levi-Schaffer, Francesca Nilsson, Gunnar Okayama, Yoshimichi Prussin, Calman Schroeder, John T. Schwartz, Lawrence B. Simon, Hans-Uwe Walls, Andrew F. Triggiani, Massimo |
| author_sort | Metcalfe, Dean D. |
| collection | PubMed |
| description | Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology. |
| format | Online Article Text |
| id | pubmed-4751725 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-47517252016-02-22 Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases Metcalfe, Dean D. Pawankar, Ruby Ackerman, Steven J. Akin, Cem Clayton, Frederic Falcone, Franco H. Gleich, Gerald J. Irani, Anne-Marie Johansson, Mats W. Klion, Amy D. Leiferman, Kristin M. Levi-Schaffer, Francesca Nilsson, Gunnar Okayama, Yoshimichi Prussin, Calman Schroeder, John T. Schwartz, Lawrence B. Simon, Hans-Uwe Walls, Andrew F. Triggiani, Massimo World Allergy Organ J Review Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology. BioMed Central 2016-02-11 /pmc/articles/PMC4751725/ /pubmed/26904159 http://dx.doi.org/10.1186/s40413-016-0094-3 Text en © Metcalfe et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Review Metcalfe, Dean D. Pawankar, Ruby Ackerman, Steven J. Akin, Cem Clayton, Frederic Falcone, Franco H. Gleich, Gerald J. Irani, Anne-Marie Johansson, Mats W. Klion, Amy D. Leiferman, Kristin M. Levi-Schaffer, Francesca Nilsson, Gunnar Okayama, Yoshimichi Prussin, Calman Schroeder, John T. Schwartz, Lawrence B. Simon, Hans-Uwe Walls, Andrew F. Triggiani, Massimo Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title_full | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title_fullStr | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title_full_unstemmed | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title_short | Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| title_sort | biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751725/ https://www.ncbi.nlm.nih.gov/pubmed/26904159 http://dx.doi.org/10.1186/s40413-016-0094-3 |
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