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Analysis of mitochondrial DNA alteration in new phenotype ACOS

BACKGROUND: Mitochondria contain their own DNA (MtDNA) that is very sensitive to oxidative stress and as a consequence could be damaged in quantity. Oxidative stress is largely recognized to play a key role in the pathogenesis of asthma and COPD and might have a role in the new intermediate phenotyp...

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Detalles Bibliográficos
Autores principales: Carpagnano, G. E., Lacedonia, D., Malerba, M., Palmiotti, G. A., Cotugno, G., Carone, M., Foschino-Barbaro, M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751730/
https://www.ncbi.nlm.nih.gov/pubmed/26867569
http://dx.doi.org/10.1186/s12890-016-0192-6