Cargando…
Dissecting Japan's Dengue Outbreak in 2014
Despite Japan's temperate climate, a dengue outbreak occurred in Tokyo for the first time in over 70 years in 2014. We dissected this dengue outbreak based on phylogenetic analysis, travel interconnectivity, and environmental drivers for dengue epidemics. Comparing the available dengue virus 1...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751952/ https://www.ncbi.nlm.nih.gov/pubmed/26711518 http://dx.doi.org/10.4269/ajtmh.15-0468 |
_version_ | 1782415656946237440 |
---|---|
author | Quam, Mikkel B. Sessions, October Kamaraj, Uma Sangumathi Rocklöv, Joacim Wilder-Smith, Annelies |
author_facet | Quam, Mikkel B. Sessions, October Kamaraj, Uma Sangumathi Rocklöv, Joacim Wilder-Smith, Annelies |
author_sort | Quam, Mikkel B. |
collection | PubMed |
description | Despite Japan's temperate climate, a dengue outbreak occurred in Tokyo for the first time in over 70 years in 2014. We dissected this dengue outbreak based on phylogenetic analysis, travel interconnectivity, and environmental drivers for dengue epidemics. Comparing the available dengue virus 1 (DENV1) E gene sequence from this outbreak with 3,282 unique DENV1 sequences in National Center for Biotechnology Information suggested that the DENV might have been imported from China, Indonesia, Singapore, or Vietnam. With travelers arriving into Japan, Guangzhou (China) may have been the source of DENV introduction, given that Guangzhou also reported a large-scale dengue outbreak in 2014. Coinciding with the 2014 outbreak, Tokyo's climate conditions permitted the amplification of Aedes vectors and the annual peak of vectorial capacity. Given suitable vectors and climate conditions in addition to increasing interconnectivity with endemic areas of Asia, Tokyo's 2014 outbreak did not come as a surprise and may foretell more to come. |
format | Online Article Text |
id | pubmed-4751952 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The American Society of Tropical Medicine and Hygiene |
record_format | MEDLINE/PubMed |
spelling | pubmed-47519522016-02-22 Dissecting Japan's Dengue Outbreak in 2014 Quam, Mikkel B. Sessions, October Kamaraj, Uma Sangumathi Rocklöv, Joacim Wilder-Smith, Annelies Am J Trop Med Hyg Articles Despite Japan's temperate climate, a dengue outbreak occurred in Tokyo for the first time in over 70 years in 2014. We dissected this dengue outbreak based on phylogenetic analysis, travel interconnectivity, and environmental drivers for dengue epidemics. Comparing the available dengue virus 1 (DENV1) E gene sequence from this outbreak with 3,282 unique DENV1 sequences in National Center for Biotechnology Information suggested that the DENV might have been imported from China, Indonesia, Singapore, or Vietnam. With travelers arriving into Japan, Guangzhou (China) may have been the source of DENV introduction, given that Guangzhou also reported a large-scale dengue outbreak in 2014. Coinciding with the 2014 outbreak, Tokyo's climate conditions permitted the amplification of Aedes vectors and the annual peak of vectorial capacity. Given suitable vectors and climate conditions in addition to increasing interconnectivity with endemic areas of Asia, Tokyo's 2014 outbreak did not come as a surprise and may foretell more to come. The American Society of Tropical Medicine and Hygiene 2016-02-03 /pmc/articles/PMC4751952/ /pubmed/26711518 http://dx.doi.org/10.4269/ajtmh.15-0468 Text en ©The American Society of Tropical Medicine and Hygiene This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Articles Quam, Mikkel B. Sessions, October Kamaraj, Uma Sangumathi Rocklöv, Joacim Wilder-Smith, Annelies Dissecting Japan's Dengue Outbreak in 2014 |
title | Dissecting Japan's Dengue Outbreak in 2014 |
title_full | Dissecting Japan's Dengue Outbreak in 2014 |
title_fullStr | Dissecting Japan's Dengue Outbreak in 2014 |
title_full_unstemmed | Dissecting Japan's Dengue Outbreak in 2014 |
title_short | Dissecting Japan's Dengue Outbreak in 2014 |
title_sort | dissecting japan's dengue outbreak in 2014 |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751952/ https://www.ncbi.nlm.nih.gov/pubmed/26711518 http://dx.doi.org/10.4269/ajtmh.15-0468 |
work_keys_str_mv | AT quammikkelb dissectingjapansdengueoutbreakin2014 AT sessionsoctober dissectingjapansdengueoutbreakin2014 AT kamarajumasangumathi dissectingjapansdengueoutbreakin2014 AT rocklovjoacim dissectingjapansdengueoutbreakin2014 AT wildersmithannelies dissectingjapansdengueoutbreakin2014 |