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Positive Selection or Free to Vary? Assessing the Functional Significance of Sequence Change Using Molecular Dynamics
Evolutionary arms races between pathogens and their hosts may be manifested as selection for rapid evolutionary change of key genes, and are sometimes detectable through sequence-level analyses. In the case of protein-coding genes, such analyses frequently predict that specific codons are under posi...
Autores principales: | Allison, Jane R., Lechner, Marcus, Hoeppner, Marc P., Poole, Anthony M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752228/ https://www.ncbi.nlm.nih.gov/pubmed/26871901 http://dx.doi.org/10.1371/journal.pone.0147619 |
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