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Structural and Functional Characterization of a Caenorhabditis elegans Genetic Interaction Network within Pathways
A genetic interaction (GI) is defined when the mutation of one gene modifies the phenotypic expression associated with the mutation of a second gene. Genome-wide efforts to map GIs in yeast revealed structural and functional properties of a GI network. This provided insights into the mechanisms unde...
Autores principales: | Boucher, Benjamin, Lee, Anna Y., Hallett, Michael, Jenna, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752231/ https://www.ncbi.nlm.nih.gov/pubmed/26871911 http://dx.doi.org/10.1371/journal.pcbi.1004738 |
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