Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility

Leukocyte immunoglobulin-like receptor A3 (LILRA3) is a soluble immune regulatory molecule primarily expressed by monocytes and macrophages. A homozygous 6.7kbp LILRA3 gene deletion that removes the first seven of its eight exons is predicted to lead to lack of LILRA3 protein, although this has not...

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Detalles Bibliográficos
Autores principales: An, Hongyan, Lim, Chai, Guillemin, Gilles J., Vollmer-Conna, Ute, Rawlinson, William, Bryant, Katherine, Tedla, Nicodemus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752247/
https://www.ncbi.nlm.nih.gov/pubmed/26871720
http://dx.doi.org/10.1371/journal.pone.0149200

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