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IL-17RA in Non-Hematopoietic Cells Controls CXCL-1 and 5 Critical to Recruit Neutrophils to the Lung of Mycobacteria-Infected Mice during the Adaptive Immune Response
During chronic infection with Mycobacterium tuberculosis (Mtb), bacilli multiplication is constrained within lung granulomas until excessive inflammation destroys the lung. Neutrophils are recruited early and participate in granuloma formation, but excessive neutrophilia exacerbates the tuberculosis...
Autores principales: | Lombard, Robin, Doz, Emilie, Carreras, Florence, Epardaud, Mathieu, Le Vern, Yves, Buzoni-Gatel, Dominique, Winter, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752258/ https://www.ncbi.nlm.nih.gov/pubmed/26871571 http://dx.doi.org/10.1371/journal.pone.0149455 |
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