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A Feature Selection Algorithm to Compute Gene Centric Methylation from Probe Level Methylation Data

DNA methylation is an important epigenetic event that effects gene expression during development and various diseases such as cancer. Understanding the mechanism of action of DNA methylation is important for downstream analysis. In the Illumina Infinium HumanMethylation 450K array, there are tens of...

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Detalles Bibliográficos
Autores principales: Baur, Brittany, Bozdag, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752315/
https://www.ncbi.nlm.nih.gov/pubmed/26872146
http://dx.doi.org/10.1371/journal.pone.0148977