Exome Sequencing in Classic Hairy Cell Leukaemia Reveals Widespread Variation in Acquired Somatic Mutations between Individual Tumours Apart from the Signature BRAF V(600)E Lesion

In classic Hairy cell leukaemia (HCLc), a single case has thus far been interrogated by whole exome sequencing (WES) in a treatment naive patient, in which BRAF V(600)E was identified as an acquired somatic mutation and confirmed as occurring near-universally in this form of disease by conventional...

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Detalles Bibliográficos
Autores principales: Weston-Bell, Nicola J., Tapper, Will, Gibson, Jane, Bryant, Dean, Moreno, Yurany, John, Melford, Ennis, Sarah, Kluin-Nelemans, Hanneke C., Collins, Andrew R., Sahota, Surinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752330/
https://www.ncbi.nlm.nih.gov/pubmed/26871591
http://dx.doi.org/10.1371/journal.pone.0149162

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