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Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III
Multiple relationships between ubiquitin-proteasome mediated protein turnover and transcriptional activation have been well documented, but the underlying mechanisms are still poorly understood. One way to induce degradation is via ubiquitination of the N-terminal α-amino group of proteins. The majo...
Autores principales: | Beaulieu, Yves B., Leon Machado, Jorge A., Ethier, Sylvain, Gaudreau, Luc, Steimle, Viktor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752451/ https://www.ncbi.nlm.nih.gov/pubmed/26871568 http://dx.doi.org/10.1371/journal.pone.0148753 |
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