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Testicular Busulfan Injection in Mice to Prepare Recipients for Spermatogonial Stem Cell Transplantation Is Safe and Non-Toxic
Current methods of administering busulfan to remove the endogenous germ cells cause hematopoietic toxicity, require special instruments and a narrow transplantation time. We use a direct testicular injection of busulfan method for preparing recipients for SSC transplantation. Male ICR mice (recipien...
Autores principales: | Qin, YuSheng, Liu, Ling, He, YaNan, Wang, Chen, Liang, MingYuan, Chen, XiaoLi, Hao, HaiSheng, Qin, Tong, Zhao, XueMing, Wang, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752460/ https://www.ncbi.nlm.nih.gov/pubmed/26871566 http://dx.doi.org/10.1371/journal.pone.0148388 |
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