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M2 macrophage polarization modulates epithelial-mesenchymal transition in cisplatin-induced tubulointerstitial fibrosis

Cisplatin-induced nephrotoxicity leaded to apoptosis of tubular epithelial cells (ECs) and tubulointerstitial fibrosis through ROS stress and inflammatory cytokines. Tubulointerstitial fibrosis caused by cisplatin might be via activation of resident fibroblasts and epithelial-mesenchymal transition...

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Detalles Bibliográficos
Autores principales:	Yu, Chia-Cherng, Chien, Chiang-Ting, Chang, Tzu-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	China Medical University 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752551/ https://www.ncbi.nlm.nih.gov/pubmed/26872813 http://dx.doi.org/10.7603/s40681-016-0005-5

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