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Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

Ebola virus (EBOV) makes extensive and intricate use of host factors in the cellular endosomal/lysosomal pathway to release its genome into the cytoplasm and initiate infection. Following viral internalization into endosomes, host cysteine proteases cleave the EBOV fusion glycoprotein (GP) to unmask...

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Detalles Bibliográficos
Autores principales:	Spence, Jennifer S., Krause, Tyler B., Mittler, Eva, Jangra, Rohit K., Chandran, Kartik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752599/ https://www.ncbi.nlm.nih.gov/pubmed/26861015 http://dx.doi.org/10.1128/mBio.01857-15

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